9. Lady Jessica Atreides
OK, so she may not be the most successful mother ever, but her son does turn out to be the Kwisatz Haderach, so that has to be worth something, right? Her influence in the Dune universe is hard to overstate, with both of her children and her grandson ruling the Empire for periods of time (in the case of her grandson Leto II, a really long time). Her ultimate legacy is tarnished a bit by her name being used by the Sisterhood as a warning to practice restraint, but at least she was remembered, right?